An Antibiotic called Minoclyine is now…
a commonly used, long-term, treatment for acne vulgaris and rosacea. It is the most lipophilic of the tetracycline, and this characteristic is responsible for its excellent skin penertration. It has been associated with discoloration of teeth, bones, oral mucosa, skin, and nail beds.
Since the 1950s, drugs from the tetracycline family have been associated with internal tooth discoloration. Once in the bloodstream, tetracycline can be incorporated in the calcification process of developing teeth. Minocycline is a second-generation derivative of tetracycline. Minocycline can lead to a green-gray or blue-gray intrinsic staining of teeth. Unlike with other tetracycline, staining occurs during and after the complete formation of eruption of teeth.. Minocycline is prescribed for long-term acne therapy in adolescents and adults, although it is being replaced by medications such as Clindamycine and isotretinoin that do not cause tooth discoloration.
If you are on minoclynine and you notice your teeth or the whites of your eyes are discoloring (grayish) then you may want to discuss this with your doctor. Some of this color changes can be permanent. Best to look into it as well.
